The 'Spiderman knocking out bully' meme comes from the 2002 movie "Spider-Man," where Peter Parker, played by Tobey Maguire, discovers his new spider-like abilities. While on a school bus, he accidentally uses his newfound strength to knock out Flash Thompson, the school bully, played by Joe Manganiello. This scene perfectly captures Peter's initial struggle to control his powers, leading to an unintended and comically exaggerated outcome. The shocked expression on Peter's face as he realizes what he's done adds to the meme's humor, making it a staple for situations where one's actions go unexpectedly overboard.