The 'Joker running with sign' meme features Joaquin Phoenix's Joker from the 2019 film 'Joker.' In a particularly memorable scene, Phoenix's character is seen running through a gritty alley before the shot zooms in on him gripping a yellow wooden sign. The intensity of the scene, combined with the chaotic and unhinged energy that Phoenix brings to the character, makes this image ripe for meme creation. It captures a moment of rebellious determination, perfect for illustrating impulsive or questionable decisions that feel both thrilling and slightly disastrous.