The Jesse Pinkman meme, featuring the iconic scene where he screams in a high-pitched voice, "You can't keep getting away with this!", originates from the critically acclaimed TV series Breaking Bad. Jesse Pinkman, played by Aaron Paul, is a character known for his intense emotions and frequent outbursts. This particular scene captures Jesse at a breaking point, overwhelmed by the injustices and chaos in his life. His voice cracking under the weight of his emotions became a perfect snapshot for internet culture, symbolizing the peak of frustration and helplessness.