The 'Get Out Awkward Handshake Rejection' meme comes from a scene in Jordan Peele's 2017 horror film, "Get Out." In this scene, Chris, played by Daniel Kaluuya, attempts to give a casual fist bump to Andre, portrayed by Lakeith Stanfield. However, Andre awkwardly shakes Chris's fist as if it were a formal handshake, creating a moment of social discomfort that resonates with viewers. This scene, set against the backdrop of an outdoor gathering, perfectly encapsulates the tension and unease that can arise from a simple social interaction gone awry. The humor and relatability of this moment have propelled it into meme stardom, particularly for its portrayal of an everyday social faux pas.