The Conan O'Brien angry meme draws its humor from a well-known clip of the famous late-night host striding with palpable irritation. Conan O'Brien, known for his quick wit and comedic timing, has become a staple in the meme world thanks to his expressive mannerisms. This particular meme captures him in a moment of pure exasperation, stomping along and knocking over objects in his path. This scene, likely from one of his comedic sketches, encapsulates the feeling of having reached the end of one's patience, resonating with anyone who has ever had to face the world in a foul mood.